山东省黑热病防治效果的免疫学评价与有关问题的探讨

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山东省黑热病于1958年达到基本消灭后,坚持监测,继续防治,自1972年以来仅查见18例因长期误诊或治而未愈的残余病人,未再出现新感染的患者;白蛉显著减少,在85%的村庄已告绝迹。为了对防治效果作进一步的评价,1989年在13个地(市)、24个县(市区)的78个乡镇进行了免疫学监测,对10239名农村居民作利什曼素皮内试验(LDT),结果30岁以下人群无1例阳性反应(0/8020),30岁以上的居民阳性率平均为4.42%(98/2219),显示黑热病的传播早已得到有效的控制。在作LDT的人群中,对1232人同时采血作间接荧光抗体试验(IFAT),结果均为阴性。 After the kala-azar disease in Shandong Province was basically eliminated in 1958, it insisted on monitoring and continued prevention and treatment. Since 1972, only 18 patients with newly-infected patients who were misdiagnosed or cured due to long-term misdiagnosis or cure were found; , 85% of the villages have been extinct. In order to further evaluate the effect of prevention and control, immunological monitoring was conducted in 78 towns and villages in 13 prefectures (cities) and 24 counties (urban districts) in 1989, and 10,339 rural residents were tested for Leishmanin intradermal test LDT). No positive reaction (0/8020) was found in people below 30 years of age, and the average positive rate was 4.42% (98/2219) in residents above 30 years old, indicating that the spread of kala-azar had been effectively controlled. In the LDT population, 1232 simultaneous blood tests for indirect fluorescent antibody test (IFAT), the results were negative.
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