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目的探讨急性心肌梗死患者 QT离散度 (QTd)的变化及氨酰心安对 QTd的影响及意义。方法选择 160例确诊为急性心肌梗死患者随机分成氨酰心安组及非氨酰心安对照组 ,分别测定其在不同时间的 QTd。结果入选前两组 QTd无差别 ,氨酰心安治疗组在用药后第 3、14、2 8天其 QTd均低于非氨酰心安组 (P<0 .0 1) ,且心率减慢 ,表明氨酰心安有减慢心率及缩短 QTd的作用。结论急性心肌梗死患者 QTd延长 ,氨酰心安可缩短 QTd,这对减少室性心律失常的发生及降低病死率有益
Objective To investigate the changes of QTd in patients with acute myocardial infarction (AMI) and the effect of Atenolol on QTd. Methods One hundred and sixty patients diagnosed as acute myocardial infarction were randomly divided into alanyl group and a-a-amicoline control group, and their QTd were measured at different time points. Results There was no difference in the QTd between the two groups before admission, and the QTd of atenolol group was lower than that of alanosine group on the 3rd, 14th and 28th day after treatment (P <0.01), and the heart rate decreased Aloxacin has heart rate and shorten the role of QTd. Conclusion Acute myocardial infarction patients QTd prolonged, atenolol can shorten the QTd, which reduce the incidence of ventricular arrhythmias and reduce the mortality benefit