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[目的]观察低分子肝素(LMWH)联合葛根素注射液(PI)治疗不稳定型心绞痛的疗效及安全性。[方法]将82例不稳定型心绞痛患者随机分为两组:对照组41例,在常规治疗的基础上加用普通肝素维持静滴,连用5日;观察组41例,在常规治疗的基础上加用葛根素500mg静滴,1次/日,疗程14天,低分子肝素5000U皮下注射,1次/12h,连用5天。[结果]低分子肝素联合葛根素能有效缓解症状、改善心电图、心肌耗氧明显下降(P<0.05)。[结论]低分子肝素联合葛根素治疗不稳定型心绞痛有效、安全。
[Objective] To observe the efficacy and safety of low molecular weight heparin (LMWH) combined with puerarin (PI) in the treatment of unstable angina pectoris. [Methods] 82 patients with unstable angina pectoris were randomly divided into two groups: control group, 41 cases, on the basis of routine treatment with unfractionated heparin to maintain intravenous infusion for 5 days; observation group, 41 cases, based on conventional treatment On the increase with puerarin 500mg intravenous infusion, 1 / day, treatment for 14 days, low molecular weight heparin 5000U subcutaneous injection, 1 / 12h, once every 5 days. [Result] Low molecular weight heparin combined with puerarin could effectively relieve symptoms and improve electrocardiogram, myocardial oxygen consumption decreased significantly (P <0.05). [Conclusion] Low molecular weight heparin combined with puerarin is effective and safe for the treatment of unstable angina pectoris.