One-pot, solvent-free and efficient synthesis of 2,4,6-triarylpyridines catalyzed by nano-titania-su

• 作 者: Elham Tabrizian Ali Amoozadeh Salman Rahmani Elham Imanifar Saeede Azhari Masoumeh Malmir
• 机 构: Department of Organic Chemistry, Faculty of Chemistry, Semnan University,
• 出 处: Chinese Chemical Letters
• 发表日期: 2015年10期
• 关键词: sulfonic titania heterogeneous ammonium One-pot aldehydes reused simplicity cata

Nano titania-supported sulfonic acid(n-TSA) has found to be a highly efficient, eco-friendly and recyclable heterogeneous nanocatalyst for the solvent-free synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenones, aryl aldehydes and ammonium acetate. This reported method illustrates several advantages such as environmental friendliness reaction conditions,simplicity, short reaction time, easy work up, reusability of catalyst and high yields of the products. One new compound is reported too. Furthermore, the catalyst could be recycled after a simple work-up, and reused at least six times without substantial reduction in its catalytic activity.

Nano titania-supported sulfonic acid (n-TSA) has found to be highly efficient, eco-friendly and recyclable heterogeneous nanocatalyst for the solvent-free synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenones This reported method shows several advantages such as environmental friendliness reaction conditions, simplicity, short reaction time, easy work up, reusability of catalyst and high yields of the products. catalyst could be recycled after a simple work-up, and reused at least six times without substantial reduction in its catalytic activity.