RETINOIC ACID NUCLEAR RECEPTOR α（RARα） PLAYS A MAJOR ROLE IN RETINOID-MEDIATED INHIBITIONOF GROWTH I

• 作 者: 邵志敏 余黎明 沈镇宙 JosephA.Fontana
• 机 构: DepartmentofSurgery
• 出 处: 中国医学科学杂志：英文版
• 发表日期: 1996年3期
• 关键词: 胸腺癌 维生素A酸受体 雌激素受体 作用机制 RXRs retinoids breast cancer nuclear receptor.

Retinoids mediate their actions via retinoic acid receptors (RARα) and retinoid X receptors (RXRs). Each of class of these nuclear retinoid receptor is further subdivided into three species narnely α，βandγ，Recently studies demonstrated that estrogen recep