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本文研究了通过胎盘和乳汁暴露铅对小鼠仔代活动性行为及中枢多巴胺水平的影响。结果表明，仔鼠血及脑中铅含量明显增加，其血铅含量与母体血铅呈正相关；低浓度铅（血铅值为１．２５μｍｏｌ／Ｌ）并不影响仔鼠大脑中多巴胺的水平，但却增加了仔鼠的站立行为；高浓度铅（血铅值为３．９４μｍｏｌ／Ｌ）不仅增加了仔鼠的活动性行为，还进一步导致中枢多巴胺水平的变化。提示：铅对行为的影响较为敏感。当多巴胺水平尚未见显著变化时，可发生行为的改变。
This article studies the effects of exposing lead through the placenta and milk to the locomotor activity and central dopamine levels in mice. The results showed that the content of lead in blood and brain of the offspring increased significantly, and the content of blood lead was positively correlated with maternal blood lead. The low concentration of lead (blood lead value 1.25μmol / L) did not affect the level of dopamine in the brain of offspring, But increased the standing behavior of offspring. High concentrations of lead (blood lead value of 3.94μmol / L) not only increased the activity of offspring mice, but also led to the change of central dopamine level. Tip: Lead is more sensitive to behavior. Changes in behavior can occur when there has not been a significant change in dopamine levels.