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目的：探索巴曲止血酶治疗急性脑血管疾病并发应激性溃疡出血的疗效。方法：５８例病人随机分为巴曲止血酶组３５例（男性２１例，女性１４例；年龄５６±ｓ１０ａ），用巴曲止血酶１ＫＵ，ｉｖ，ｂｉｄ；西咪替丁组２３例（男性１３例，女性１０例；年龄５７±１０ａ），用西咪替丁０．４ｇ，ｉｖｄｒｉｐ，ｂｉｄ，均５ｄ为一个疗程。结果：巴曲止血酶组总有效率８９％，优于西咪替丁组的６１％（Ｐ＜０．０５）；前组神经功能缺损积分值较后组下降显著（Ｐ＜０．０５），与脑出血、脑缺血无关。治疗期间未发现任何不良反应。结论：该药不仅有显著局部止血作用，且对急性脑血管疾病的神经功能缺损有明显的改善作用
Objective: To explore the efficacy of batroxobin in the treatment of acute cerebrovascular disease complicated by stress ulcer bleeding. Methods: Fifty-eight patients were randomly divided into batroxobin group (21 males and 14 females; age 56 ± s10a), with batroxobin 1KU, iv, bid and cimetidine 23 13 cases, 10 females; age 57 ± 10a), with cimetidine 0.4g, ivdrip, bid, were 5d for a course of treatment. Results: The total effective rate of batroxobin group was 89%, which was superior to that of cimetidine group (61%, P <0.05). The integral value of neurological deficit in the former group decreased significantly compared with the latter group (P <0.05) , With cerebral hemorrhage, cerebral ischemia has nothing to do. During the treatment did not find any adverse reactions. Conclusion: The drug not only has significant local hemostasis, but also has a significant effect on neurological deficits in acute cerebrovascular diseases