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钙离子对心肌的功能很为重要.鉴于以往研究中有若干因素使某些结果的解释发生困难,本文的实验设计有下列三项要求:(1)血浆钙离子的改变可同时影响心脏和周围血管的功能,因此在研究不同钙离子浓度对心室功能的影响时,对血流动力学必须加以控制.(2)收集血流动力学资料时,必须测定血浆钙离子浓度并维持其稳定.(3)为使获得的资料可供临床应用,实验中血浆钙离子浓度的变化必须在临床变化的范围内.方法:杂种犬13条,在静脉麻醉下作气管插管,机械控制呼吸,胸骨正中劈开切口进胸.经右内乳
Calcium ions are very important for the function of the myocardium. In view of the fact that there are several factors in previous studies that make it difficult to interpret some of the results, the experimental design in this article has the following three requirements: (1) Changes in plasma calcium affect both the heart and the surroundings Blood vessel function, hemodynamics must be controlled when studying the effect of different calcium concentrations on ventricular function. (2) Plasma hemoglobin concentration must be measured and maintained steady when collecting hemodynamic data. 3) In order to make the data available for clinical application, the changes of plasma calcium concentration in the experiment must be within the range of clinical changes.Methods: 13 hybrid dogs, tracheal intubation under intravenous anesthesia, mechanical control of breathing, Split the incision into the chest