论文部分内容阅读
目的探讨不同血钠浓度对重度颅脑损伤预后的影响。方法选取2013年1月—2014年1月宿州市立医院神经外科住院部的重度颅脑损伤患者113例,将患者按不同血钠浓度分为低血钠组(血钠<135mmol/L,30例)、正常血钠组(135mmol/L≤血钠≤145mmol/L,52例)和高钠血症组(血钠>145mmol/L,31例)。3组患者均给予对症治疗,治疗后比较3组患者的住院时间、格拉斯哥昏迷评分法(GCS)评分、格拉斯哥预后分级(GOS)和病死率。结果 3组患者住院时间比较,差异无统计学意义(P>0.05);3组患者入院时、入院后7d和入院后21d GCS评分比较,差异有统计学意义(P<0.05)。正常血钠组恢复良好率优于低血钠组及高血钠组,差异有统计学意义(P<0.05)。结论血钠浓度可初步作为重度颅脑损伤预后的评估指标之一。
Objective To investigate the effect of different concentrations of serum sodium on the prognosis of severe craniocerebral injury. Methods From January 2013 to January 2014, 113 patients with severe craniocerebral injury in Department of Neurosurgery, Suzhou Municipal Hospital were enrolled. Patients were divided into low sodium group (serum sodium <135mmol / L, 30 cases ), Normal serum sodium group (135 mmol / L≤were sodium≤145mmol / L, 52 cases) and hypernatremia group (serum sodium> 145mmol / L, 31 cases). Three groups of patients were given symptomatic treatment. After treatment, hospital stay, Glasgow coma scale (GCS) score, Glasgow prognostic grade (GOS) and mortality were compared between the three groups. Results There was no significant difference in hospitalization time between the three groups (P> 0.05). There were significant differences in GCS scores between the three groups on admission, 7 days after admission and 21 days after admission (P <0.05). The recovery rate of normal sodium group was better than that of hyponatremia group and hypernatremia group, the difference was statistically significant (P <0.05). Conclusion Serum sodium concentration may be used as a predictor of prognosis in severe craniocerebral injury.