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目的:分析AML-M4、M5患者的临床和免疫学特征。万法:总结了75例患者的血液学和临床特征,并用活细胞间接免疫荧光法检测了其中39例患者的细胞免疫表型,着重分析了CD7+AML在这二类AML中的发生率、临床特征及预后。结果:这两类白血病的HLA-DR、CD38、CD34阳性率很高,分别为91.43%,85.19%和65.63%,CD7阳性率为35.90%;结论:M4、M5这二种亚型有不同于其它AML亚型的临床,血液学和生物学特征。
Objective: To analyze the clinical and immunological features of AML-M4 and M5 patients. Wan Fa: We summarized the hematological and clinical features of 75 patients and examined the cellular immune phenotypes of 39 patients with live cell indirect immunofluorescence. We focused on the incidence of CD7+ AML in these two types of AML. Clinical features and prognosis. Results: The positive rates of HLA-DR, CD38 and CD34 in these two types of leukemia were 91.43%, 85.19% and 65.63%, respectively. The positive rate of CD7 was 35.90%. Conclusion: M4, M5 These two subtypes have clinical, hematological, and biological characteristics that are different from other AML subtypes.