论文部分内容阅读
14例肺癌活检组织按照超微结构分类指标进行电镜观察。结果：鳞癌4例，腺鳞癌5例，腺癌2例，小细胞癌3例。与光镜观察诊断结果相比，两者完全相符者8例，占57％。原光镜诊为鳞癌8例，无腺鳞癌；而电镜下鳞癌4例，腺鳞癌5例，上升为35％。两者诊断的分歧明显。电镜还观察到在同一个癌细胞内出现鳞性──神经内分泌性及腺性──鳞性的双向分化。表明对癌细胞的多能分化和异质性的观察电镜优于光镜。
14 cases of lung cancer biopsy were observed by electron microscopy according to the ultrastructural classification criteria. Results: There were 4 cases of squamous cell carcinoma, 5 cases of adenosquamous carcinoma, 2 cases of adenocarcinoma, and 3 cases of small cell carcinoma. Compared with the results of light microscope observation and diagnosis, there were 8 cases in total, accounting for 57%. The original light microscope diagnosis of squamous cell carcinoma in 8 cases, no adenosquamous carcinoma; and electron microscopy in 4 cases of squamous cell carcinoma, adenosquamous carcinoma in 5 cases, increased to 35%. The differences between the two diagnoses are obvious. Electron microscopy also observed the squamous, neuroendocrine and glandular, squamous bidirectional differentiation within the same cancer cell. Observing the pluripotent differentiation and heterogeneity of cancer cells is superior to light microscopy.