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Sinus histiocytosis with massive lymphadenopathy or Rosai- Dorfman disease i s a non-Langerhans cell histiocytosis of unknown etiolosy. The most characteri stic feature is lymphadenopathy, especially that of cervical lymph nodes. In app roximately 40% of patients there are extranodal manifestations of the disease. Skin is the most commonly affected organ (27% ). We report a 79- year-old f emale patient with purely cutaneous manifestations. This form of the disease is a very rare differential diagnosis in dermatology.
Sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease isa non-Langerhans cell histiocytosis of unknown etiolosy. The most characteri stic feature is lymphadenopathy, especially that of cervical lymph nodes. In app roximately 40% of patients there are extranodal manifestations of the disease. Skin is the most commonly affected organ (27%). We report a 79- year-old f emale patient with purely cutaneous manifestations. This form of the disease is a very rare differential diagnosis in dermatology.