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患RDS的未成熟儿脑血流速度与脑室出血有明显的联系。已证明,脑血流速度的波动直接反映了体循环压波动。这种变化的多样性和不规则性的原因还不清楚,可能与婴儿血管舒缩性、呼吸肌的活动性、通气的正压作用、静脉回流阻力、心室顺应性的改变及其它心血管因素有关。本文对气管插管的RDS患儿动脉压波动的机制加以探讨。材料和方法 5名经机械通气的RDS未成熟儿,胎龄为30±3周,体重为1100±150g。实验于生后12小时之内进行,连续观测2～3小时。其动脉血压波动均持续30分钟以上。经脐动脉导管测定腹主动脉压。2次连续搏动的动脉压变化在10%以上者定为动脉压波动。用连续波动20～45次的波形进行分析及计算,变异系数=标准差/平均值×100%。经测定,所
There is a clear relationship between cerebral blood flow velocity and ventricular hemorrhage in immature infants with RDS. It has been demonstrated that fluctuations in cerebral blood flow velocity directly reflect systemic pressure fluctuations. The reasons for the diversity and irregularity of such changes are unclear and may be related to infantile vasomotion, respiratory muscle activity, positive pressure effects of ventilation, venous return resistance, changes in ventricular compliance and other cardiovascular factors related. This article explores the mechanism of arterial pressure fluctuations in children with RDS after endotracheal intubation. MATERIALS AND METHODS Five mechanically ventilated RDS immature infants, gestational age 30 ± 3 weeks, and body weight 1100 ± 150 g. Experiments within 12 hours after birth, continuous observation of 2 to 3 hours. The arterial blood pressure fluctuations were sustained more than 30 minutes. The abdominal aortic pressure was measured by umbilical artery catheter. Two consecutive pulsatile arterial pressure changes in more than 10% as arterial pressure fluctuations. With continuous fluctuations of 20 to 45 times the waveform analysis and calculation, coefficient of variation = standard deviation / average × 100%. After determination, the