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目的比较强化免疫前后福建省的麻疹流行病学特征。方法比较2009年麻疹疫苗强化免疫前后3年福建省麻疹发病情况。结果福建省强化免疫前后3年麻疹发病率分别为4.65/10万、5.49/10万、3.67/10万、0.28/10万、0.06/10万和0.24/10万,平均发病率分别为4.60/10万和0.19/10万。强化免疫前后季节和地区分布没有发生改变,但发病年龄构成发生变化,强化免疫前8月龄~14岁儿童麻疹病例占总病例数的56.51%,强化免疫后非免疫目标人群病例占病例总数的70.42%。免疫空白病例仍然是发病的重点人群。结论麻疹疫苗强化免疫使麻疹发病年龄特征发生改变,但对季节和地区分布影响不大。
Objective To compare the epidemiological characteristics of measles in Fujian before and after intensive immunization. Methods The incidence of measles in Fujian Province before and after 2009 was compared with that of measles vaccine in 2009. Results The incidence of measles in Fujian Province before and after three years of intensive immunization were 4.65 / 100,000, 5.49 / 100,000, 3.67 / 100,000, 0.28 / 100,000, 0.06 / 100,000 and 0.24 / 100,000, respectively. The average incidence was 4.60 / 100,000 and 0.19 / 100,000. There was no change in the seasonal and regional distribution before and after intensive immunization, but the age composition of the patients changed. The measles cases of children aged 8 months to 14 years before intensive immunization accounted for 56.51% of the total number of cases. The number of nonimmunized target population after intensive immunization accounted for the total number of cases 70.42%. Immune blank cases are still the focus of the crowd. Conclusion The measles vaccine immunization has changed the age characteristics of measles but has little effect on the seasonal and regional distribution.