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目的:讨论角化棘皮瘤的临床病理表现以及诊断和鉴别诊断。方法:分析角化棘皮瘤的临床及病理表现。结果:分析我中心1973～1995年病理确诊的角化棘皮瘤的临床病理表现。临床上:短期迅速增大,呈脐样外观,中央结痂。组织病理:中央充满角化过度或不全的物质,似火山口样,基底完整,病变可扩张至实质层。结论:角化棘皮瘤是表皮样增生性疾病,是假性癌样增生的特殊类型,它与其它肿瘤有着不同的临床与组织病理特点,并与眼部其他肿物相鉴别。眼科学报1997;13;217—218。
Objective: To discuss the clinicopathological manifestations and diagnosis and differential diagnosis of keratoacanthoma. Methods: The clinical and pathological findings of keratoacanthoma were analyzed. Results: The clinicopathological features of keratoacanthoma confirmed pathologically in our center from 1973 to 1995 were analyzed. Clinically: short-term rapid increase in umbilical appearance, the central scab. Histopathology: Central full of hyperkeratosis or incomplete material, like a crater-like, complete substrate, lesions can be expanded to the real layer. Conclusion: Keratoacanthoma is a special type of epidermoid hyperplasia and is a kind of pseudo-cancerous hyperplasia. It has different clinical and histopathological features compared with other tumors and is distinguished from other tumors in the eye. Journal of Ophthalmology 1997; 13; 217-218.