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既往对重度心功不全时使用心痛定在代谢、血气分析等方面进行的研究很少。作者对重度心功不全患者(按 NYHA 分类属心功Ⅳ级)舌下含服心痛定1小时后(即血液动力学最大疗效),从代谢、交感神经、儿茶酚胺水平、肾素活性和血气等方面进行研究,证实了心痛定的有效性。本文分析了重度心功不全9例,男4例,女5例,平均年龄71岁。肺毛细血管楔压(PCWP)均在19mmHg 以上,并伴有不同程度的肺水肿。其中急性心肌梗塞5例,陈旧性心肌梗塞伴室壁瘤1例,高血压性心脏病2例,扩张型心肌
Previous studies on the use of nifedipine in patients with severe cardiac insufficiency had little research in metabolism and blood gas analysis. The author of patients with severe cardiac insufficiency (NYHA classification according to NYHA level) sublingual convulsion determined 1 hour (ie, the maximum hemodynamic effect), from the metabolism, sympathetic nerve, catecholamine levels, renin activity and blood gas, etc. Research, confirmed the validity of the heartache. This article analyzes 9 cases of severe cardiac insufficiency, 4 males and 5 females, with an average age of 71 years. Pulmonary capillary wedge pressure (PCWP) were above 19mmHg, accompanied by varying degrees of pulmonary edema. Including 5 cases of acute myocardial infarction, old myocardial infarction with aneurysm in 1 case, 2 cases of hypertensive heart disease, dilated myocardium