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我院自1985年9月至1987年5月用胎肝细胞悬液输注(FLT)治疗再障40例,输注胎肝细胞167次,现报告如下。资料与方法40例中男27例,女13例。年龄2.5～14岁。其中慢性26例,急性14例(包括纯红再障2例)。治前病程在半月～8年,平均2年。本组病例均符合廓坊会议关于再障的诊断及疗效标准。方法:所用胎肝取自健康孕妇经水囊引产所生胎龄为4～5月的胎儿,取出后用ACD保养液或RPMI1640保养液制成胎肝单细胞悬液(标出有核细胞总数),内加地塞米松5mg 于1小时内静脉滴注。5例同时应用胎儿胸腺细胞。输注前后分别用琥珀氢化考的松25mg 静注。滴注次日给予强的松1 mg/kg/日口服两
Our hospital from September 1985 to May 1987 with fetal liver cell suspension infusion (FLT) treatment of aplastic anemia in 40 cases, infusing fetal liver cells 167 times, are as follows. Materials and Methods 40 cases of male 27 cases, 13 females. Age 2.5 to 14 years old. Among them, 26 cases were chronic and 14 cases were acute (including 2 cases with pure red aplasia). Pre-course of disease in half months ~ 8 years, an average of 2 years. This group of patients are in line with contour Fang meeting on aplastic anemia diagnosis and efficacy standards. Methods: Fetal liver was taken from fetus with gestational age of 4-5 months from healthy pregnant women induced by water bag. After removal, the fetal liver single cell suspension (labeled with total number of nucleated cells) was prepared with ACD maintenance solution or RPMI1640 maintenance solution ), Plus dexamethasone 5mg intravenous infusion within 1 hour. 5 cases of fetal thymocytes at the same time. Before and after infusion, respectively, with amber hydrocortisone 25mg intravenous injection. Dosing the day after giving prednisone 1 mg / kg / day oral two