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全胃肠外营养(Total Parenteral nutrition,简称TPN)已被接受为不能经口摄食、危重或营养不足病人提供营养的一项治疗步骤。本文研究含有葡萄糖、氨基酸、电解质和微量元素的TPN 溶液的长期稳定性,并为在家庭接受TPN 的病人规定有效期限。在洁净室内的层流操作台上将各种溶液(氨基酸溶液混合物、25%葡萄糖液、葡萄糖、电解质和微量元素溶液)灌入3升聚氯乙烯袋中,混合后置4°贮藏。在即刻,7、14和28天,3和6个月无菌取样。用氨基酸自动分析仪和Beckman-25型分光光度计分别测定各个氨
Total parenteral nutrition (TPN) has been accepted as a treatment step for nourishing patients who can not be orally ingested, critically ill or undernourished. This article studies the long-term stability of TPN solutions containing glucose, amino acids, electrolytes, and trace elements and provides for a life-time limit for patients receiving TPN in the home. Various solutions (amino acid solution mixture, 25% dextrose, dextrose, electrolytes and trace element solutions) were poured into a 3 liter polyvinyl chloride bag on a laminar flow handling station in a clean room and mixed for 4 ° storage. Immediate, 7, 14 and 28 days, 3 and 6 months aseptic sampling. Each of the ammonia was determined by an automatic amino acid analyzer and a Beckman-25 spectrophotometer