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目的探讨吗啡经皮下持续泵入在晚期癌痛患者镇痛中的应用价值。方法选取2014年1月至2016年1月间于抚顺市中心医院接受治疗的55例晚期癌痛患者作为研究对象,所有患者均经皮下持续泵入吗啡,观察患者治疗前后疼痛情况、生命质量及不良反应发生情况。结果治疗后,55例晚期癌痛患者疼痛视觉模拟量表(VAS)评分与治疗前比较显著降低,Karnofsky功能状态(KPS)评分明显高于治疗前,差异均有统计学意义(均P<0.05);患者疼痛缓解率为94.5%,不良反应发生率为25.5%。结论经皮下持续泵入吗啡对于晚期癌痛患者具有良好的镇痛效果,且安全性较高。
Objective To investigate the value of continuous subcutaneous morphine injection in patients with pain in patients with advanced cancer. Methods 55 patients with advanced cancer pain treated in Fushun Central Hospital from January 2014 to January 2016 were enrolled in this study. All patients were continuously injected with morphine via subcutaneous injection. The pain, quality of life, Adverse reactions occurred. Results After treatment, VAS scores of 55 patients with advanced cancer pain were significantly lower than those before treatment, Karnofsky functional status (KPS) scores were significantly higher than those before treatment (all P <0.05 ). The pain relief rate was 94.5% and the adverse reaction rate was 25.5%. CONCLUSION: Continuous percutaneous subcutaneous injection of morphine has a good analgesic effect in patients with advanced cancer pain and is safe.