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肌红蛋白(Mb)可用于诊断急性心肌梗塞,与肾功能不全的关系也曾有报道,但在肾病早期,肾功能正常时,Mb的变化鲜见报道。本文分析了1994年6月～1996年3月我院48例住院肾病患者的血Mb,发现肾功能正常组与常人之间,肾功能不全组与肾功能正常组之间均有显著差异,提示Mb对早期肾衰是个敏感指标,并随着肾功能恶化进一步升高。 对象和方法 一、对象: (一)肾病患者肾功能不全组:24例(男14例,女10例),平均年龄42岁(29～71岁),先后2次化验血Cr>133μmol/L)。其中慢性肾炎10例,慢性肾盂肾炎4例,肝肾综合征4例,镇痛剂肾病1例,Ⅱ型肾病综合征1例,尿酸肾病3例,喃氟啶中毒1例。 (二)肾病患者肾功能正常组:24例(男11例,女13例),平均年龄30岁(14～67岁)其中Ⅰ型肾病综合征8例。慢性肾炎2例,尿酸肾症1例。慢性肾盂肾炎
Myoglobin (Mb) can be used to diagnose acute myocardial infarction, and renal insufficiency has also been reported in the relationship, but in early nephropathy, normal renal function, Mb changes rarely reported. This article analyzes the June 1994 ~ March 1996 in our hospital 48 cases of hospitalized patients with nephropathy blood Mb found normal renal function between groups and normal, renal insufficiency group and normal renal function between groups were significantly different, suggesting Mb is a sensitive indicator of early renal failure and further increases with worsening renal function. Subjects and Methods 1. Subjects: (1) Renal insufficiency group: 24 cases (14 males and 10 females) with an average age of 42 years (ranging from 29 to 71 years). Blood samples were collected twice a day for Cr> 133μmol / L ). Including chronic nephritis in 10 cases, 4 cases of chronic pyelonephritis, hepatorenal syndrome in 4 cases, 1 case of analgesic nephropathy, 1 case of type II nephrotic syndrome, uric acid nephropathy in 3 cases, 1 case of fluoropyronium poisoning. (B) of patients with normal kidney function group: 24 cases (11 males and 13 females), mean age 30 years (14 to 67 years), including type I nephrotic syndrome in 8 cases. 2 cases of chronic nephritis, 1 case of uric acid and kidney disease. Chronic pyelonephritis