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抗癌药和免疫抑制剂氯(合)霉素、保太松、砷、磺胺药、氨基比林、扑热息痛及农药二二三(DDT)和乐果等药物可引起白血病。由乙双吗琳引起急性白血病国内报告尚少。最近我院遇到一例银屑病长期服用乙双吗啉后发生急性早幼粒细胞性白血病。患者男性,40岁,驾驶员。因不规则发热半月余伴白细胞减少,于1987年6月18日入院。1967年患牛皮癣,近年来一直服用乙双吗啉,每次二片,每日三次,总剂量438g,无特殊药物及毒物接触史,家族中无类似病史。
Anticancer drugs and immunosuppressants such as chloramphenicol, fentanyl, arsenic, sulfonamides, aminopyrine, paracetamol, and DDT and dimethoate cause leukemia. Domestic reports of acute leukemia caused by procarbazine are still low. Recently encountered in our hospital, a case of long-term use of psoriasis B double morphine occurred after acute promyelocytic leukemia. Male patient, 40 years old, pilot. Due to irregular fever more than half with leukopenia, on June 18, 1987 admission. In 1967 suffering from psoriasis, B-morphine has been taking in recent years, each two tablets, three times a day, the total dose of 438g, no special drugs and toxic exposure history, the family has no similar history.