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钙通道阻滞剂治疗成人高血压,在欧洲及美国已大量运用,但治疗小儿高血压的报导少。现用的3种钙通道阻滞剂中(即硝苯吡啶、异搏定、硫氮唑酮)硝苯吡啶的抗高血压作用最强,经舌下含化或口服后吸收快,且很快产生效应。作者对20例高血压的小儿,用硝苯吡啶治疗。病儿的年龄为14个月~14岁,平均6.7岁,高血压的病因有膜性增殖性肾小球肾炎4例,急性链球菌感染后
Calcium channel blockers for the treatment of adult hypertension, have been widely used in Europe and the United States, but the treatment of pediatric hypertension less. Of the three calcium channel blockers currently in use (ie, nifedipine, verapamil, thiadiazole) nifedipine has the strongest antihypertensive effect and absorbs rapidly after sublingual or oral administration and is very fast Faster effect. The author of 20 cases of hypertensive children treated with nifedipine. Sick children aged 14 months to 14 years, mean 6.7 years, the cause of hypertension with membranous proliferative glomerulonephritis in 4 cases, after acute streptococcal infection