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目的探讨重症手足口病患儿脑脊液特点。方法回顾性分析52例重症手足口病患儿入院后1～4天行脑脊液检查的实验室资料。结果重症手足口病患儿脑脊液生化、细胞数及分类,基本符合病毒性脑炎的脑脊液改变,部分危重症患儿脑脊液糖定量、蛋白定量及细胞数明显升高。结论重症手足口病患儿脑脊液阳性率高,因此对有神经系统症状及体征患儿行脑脊液检查,对重症手足口病患儿早期诊断及病情、疗效和预后的估计有一定意义。
Objective To investigate the characteristics of cerebrospinal fluid in children with severe hand-foot-mouth disease. Methods A retrospective analysis of 52 cases of severe hand-foot-mouth disease in children 1 to 4 days after admission cerebrospinal fluid laboratory data. Results Cerebrospinal fluid biochemistry, cell number and classification in critically ill hand-foot-mouth disease patients were basically consistent with cerebrospinal fluid changes of viral encephalitis. The cerebrospinal fluid glucose, protein quantitation and cell number of some critically ill children were significantly increased. Conclusions The positive rate of cerebrospinal fluid in children with severe hand-foot-mouth disease is high. Therefore, cerebrospinal fluid examination in children with neurological symptoms and signs is of certain significance in the early diagnosis, severity, prognosis and prognosis of severe hand-foot-mouth disease in children.