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目的:观察清热化痰汤联合常规疗法治疗重型颅脑损伤合并院内获得性肺炎患者的临床疗效。方法:将60例患者随机分为治疗组和对照组各30例。对照组按目前西医治疗及护理常规进行干预,治疗组在对照组治疗基础上加用清热化痰汤,10天为1疗程。观察并记录患者的机械通气时间、住ICU时间以及1月生存率、神经系统格拉斯哥评分(GCS)。比较2组的肺炎临床疗效和中医临床疗效。结果:治疗组的机械通气时间、住ICU时间均短于对照组(P<0.05);2组1月生存率、神经系统GCS比较,差异均无显著性意义(P>0.05)。肺炎临床疗效总有效率治疗组为96.7%,对照组为80.0%,2组比较,差异有显著性意义(P<0.05)。中医临床疗效总有效率治疗组为96.7%,对照组为76.7%,2组比较,差异有显著性意义(P<0.05)。结论:清热化痰汤联合常规疗法对重型颅脑损伤合并院内获得性肺炎患者有确切疗效。
Objective: To observe the clinical efficacy of Qingre Huatan Decoction combined with conventional therapy in patients with severe traumatic brain injury complicated with acquired pneumonia. Methods: 60 patients were randomly divided into treatment group and control group, 30 cases each. The control group according to the current Western medicine treatment and nursing routine intervention, the treatment group in the control group based on the treatment plus Qingre Huatan soup, 10 days for a course of treatment. Patients were observed and recorded mechanical ventilation time, ICU stay in life and January survival, the Glasgow Neurological Score (GCS). The clinical efficacy and clinical efficacy of pneumonia in two groups were compared. Results: The duration of mechanical ventilation and ICU stay in the treatment group were shorter than those in the control group (P <0.05). There was no significant difference in survival rate and GCS between the two groups in January (P> 0.05). The total effective rate of clinical efficacy of pneumonia was 96.7% in the treatment group and 80.0% in the control group. There was significant difference between the two groups (P <0.05). The total effective rate of clinical efficacy of traditional Chinese medicine treatment group was 96.7%, 76.7% in the control group, the two groups, the difference was significant (P <0.05). Conclusion: Qingre Huatan Decoction combined with conventional therapy for severe craniocerebral injury with hospital acquired pneumonia in patients with the exact effect.