论文部分内容阅读
谷维素系阿魏酸与不同三萜烯酯的混合物,临床上广泛用于调节植物神经功能。其质量标准收载于1989年《卫生部药品标准》(化学药品及制剂)第一册。含量测定标准采用取本品细粉适量,以正庚烷为溶剂,加热溶解,紫外法测定的方法。但日常检验中发现,常有测定结果不稳定的现象(因谷维素在正庚烷中微溶)。尤其是取含量测定(若溶解不好)的溶液做紫外鉴别时,波长(291±1)nm不出现峰。关于溶解方法的改进有报道先加入氯仿溶解,再取续滤液2
Oryzanol is a mixture of ferulic acid with different triterpene esters and is widely used in clinical practice to regulate autonomic function. Its quality standards are contained in the 1989 “Ministry of Health Drug Standards” (chemical drugs and preparations) first. Determination of the content of this product using the amount of fine powder to n-heptane as a solvent, dissolved by heating, UV method for the determination. However, the daily test found that often unstable test results (due to oryzanol in n-heptane slightly soluble). In particular, the determination of the content (if not well dissolved) solution to do UV identification, the wavelength (291 ± 1) nm peak does not appear. On the improvement of the dissolution method has been reported first added chloroform dissolved, then take the filtrate 2