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目的:评价窦性心律（窦律）伴完全性左束支传导阻滞（CLBBB）的扩张型心肌病（DCM）患者接受心脏再同步治疗（CRT）的远期效果。方法:连续入组2013年1月至2016年12月在中国医学科学院阜外医院单中心诊断为DCM且同时具有窦律伴CLBBB、QRS时限≥150 ms、心功能Ⅱ~Ⅲ级（NYHA分级）、左心室射血分数（LVEF）≤35%并接受了CRT植入治疗的患者。术后每3~6个月门诊或电话随访1次，优化CRT参数以及药物治疗方案，并在随访结束时根据患者对CRT的应答性分组。结果:入组112例患者，随访（38.2±7.4）个月后，46例（46/112，41.1%）患者表现为CRT超应答，27例（27/112，24.1%）患者表现为CRT无应答。共发生33例心血管事件，21例器械相关并发症。心血管事件的首位原因为心房颤动（17/33，51.5%）。无事件存活患者87例（87/112，77.7%），无事件生存时间为（44.0±1.8）个月。无应答组与有应答组各有13例和12例患者[（13/27，48.1%）对（12/85，14.1%）n P<0.01]，分别发生心血管事件19例和14例，无应答组与有应答组患者的无事件生存时间分别为（31.0±4.6）个月和（48.1±1.6）个月（n P<0.01）。n 结论:在接受CRT伴CLBBB的DCM患者中，无应答率较低，超应答率较高。心血管事件中最常见的为心房颤动，无应答组患者的心血管事件发生率明显高于有应答组。“,”Objective:To investigate the longn -term effect of cardiac resynchronization therapy (CRT) in patients with dilated cardiomyopathy (DCM) with sinus rhythm and complete left bundle branch block (LBBB) .n Methods:From January 2013 to December 2016 in Fuwai Hospital, the patients who were diagnosed with DCM in our center and met the following criteria were recruited in our study: ①with sinus rhythm and complete LBBB and QRS duration ≥150 ms; ②New York Heart Association (NYHA) functional class Ⅱ~Ⅲ; ③left ventricular ejection fraction (LVEF) ≤35%; ④received CRT device implantation. All patients were followed up every 3 to 6 months to optimize the setting of CRT device and medication, and divided into two groups at the end of follown -up, responders and nonn - responders.n Results:One hundred and twelve patients were enrolled and followed up for (38.2±7.4) months. Among them, 46 (46/112, 41.1%) were supern -responders and 27 (27/112, 24.1%) were nonn -responders. A total of 33 cardiovascular events and 21 device related complications were recorded. The main cause of cardiovascular events was atrial fibrillation (17/33, 51.5%) . 87 patients (87/112, 77.7%) were cardiovascular eventn -free and the mean event free survival time was (44.0±1.8) months. 19 and 14 cardiovascular events occurred in13 of nonn -responders and 12 of responders (13/27, 48.1% vs. 12/85, 14.1%, n P<0.01) , respectively. The mean eventn -free survival time in nonn -responders and responders were (31.0±4.6) months and (48.1±1.6) months in responders (n P<0.01) , respectively.n Conclusion:In DCM patients received CRT with complete LBBB, the proportion of nonn -responders was relatively low, while that of supern -responders was high. Atrial fibrillation was the most common cardiovascular event. The incidence of cardiovascular events in nonn -responders was significantly higher than that in responders.n