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通过实验性动物白念珠菌全身感染，研究在免疫功能低下状态，抗真菌经单纯治疗和与中药方剂十全大补汤伍用，其疗效的差异。实验结果证明：十全大补汤无直接抗真菌活性；抗真菌药对处于免疫功能低下状态的动物，其疗效也不十分理想。抗真菌药在治疗全身白念珠菌感染时，如用十全大补汤，通过后者ＢＲＭ样作用，可改善机体免疫状态，从而提高抗真菌药的疗效，与单纯使用抗真菌治疗有明显差异（Ｐ＜０．０５）。据此可以认为：处于免疫功能低下的机体，一旦感染真菌，在抗真菌治疗同时伍用十全大补汤有利于提高抗真菌药物的疗效。
Through the experimental animal Candida albicans systemic infection, the study on the immune function of the low state, anti-fungal treatment and the use of traditional Chinese medicine prescription Shiquan Dabu Tang Tang, its efficacy differences. The experimental results show that: Shiquandabutang has no direct antifungal activity; antifungal agents are not very effective for animals in immunocompromised states. In the treatment of whole body Candida albicans infection, antifungal drugs, such as Shiquandabutang, through the latter BRM-like role, can improve the body’s immune status, thereby increasing the efficacy of antifungal drugs, and the use of antifungal treatment is significantly different (P<0.05). Based on this, it can be considered that: In the body with low immune function, once infected with fungi, the use of Shiquandabutang at the same time in the anti-fungal treatment will help improve the efficacy of anti-fungal drugs.