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1.皮质甾醇 包括地塞米松(氟米松)、氢化可的松和泼尼松。 大剂量长期应用可能导致过期妊娠、胎儿宫内发育迟缓、死胎发病率增高。在用于预防发生新生儿呼吸窘迫综合症(RDS),给有可能早产的母亲使用此药时,应按照以下原则:(1)治疗开始后24小时内可能会分娩的患者不能使用。(2)妊娠已过34周,用药也没有显者疗效者不用。(3)已经破膜者没有必要使用。因为羊膜过早的破裂之后,RDS的发生率就会降低。
1. Corticosteroids include dexamethasone (flumethasone), hydrocortisone and prednisone. Long-term high-dose application may lead to outdated pregnancy, intrauterine growth retardation, increased morbidity of stillbirth. When used in the prevention of neonatal respiratory distress syndrome (RDS) and in mothers with potential preterm birth, the following guidelines should be followed: (1) Patients who may be delivered within 24 hours after the start of treatment should not be used. (2) Pregnancy has passed 34 weeks, medication did not significantly effect those who do not. (3) those who have broken the film is not necessary to use. Because premature rupture of amniotic membrane, the incidence of RDS will be reduced.