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目的探讨新乡市第二人民医院46例中晚期非小细胞肺癌纵隔淋巴结合理的手术清扫范围和临床意义。方法回顾性分析新乡市第二人民医院2009年1月至2010年8月收治的46例中晚期非小细胞肺癌纵隔淋巴结清扫手术。结果本组共发现共清除纵隔淋巴结262组,病理证实有转移的90组,占34.3%。跳跃性N2在鳞癌和腺癌发生率的差别经检验无统计学意义(P>0.05)。结论非小细胞肺癌患者的淋巴结转移具有跳跃性和多发性的特点,只有广泛清扫纵隔淋巴结才有可能达到根治,临床意义重大。
Objective To investigate the range and clinical significance of surgical dissection of mediastinal lymph nodes in 46 patients with advanced non-small cell lung cancer of Second People’s Hospital of Xinxiang City. Methods A retrospective analysis of the Second People’s Hospital of Xinxiang City from January 2009 to August 2010 admitted to 46 cases of advanced non-small cell lung cancer mediastinal lymph node dissection. Results A total of 262 mediastinal lymph nodes were found in this group, of which 90 were confirmed as pathologically confirmed (34.3%). There was no significant difference in the incidence of skip N2 between squamous cell carcinoma and adenocarcinoma (P> 0.05). Conclusion Lymph node metastasis in patients with non-small cell lung cancer is characterized by leaping and multiple. Only radical dissection of mediastinal lymph nodes can be achieved. It is of great clinical significance.