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目的观察替米沙坦治疗老年原发性高血压病(EH)的临床疗效。方法80例老年EH患者服用替米沙坦80mg,1次/d,疗程4周。结果治疗4周后与治疗前比较,患者血压明显下降,治疗前为(166.25±13.78)/)85.65±85.65)mmHg,治疗后降为(130.34±8.67)/(71.10±6.28)mmHg(P<0.01)。脉压亦有明显缩小(P<0.01),24h动态血压计算降压谷峰比值>65%。结论替米沙坦治疗老年EH安全有效。
Objective To observe the clinical efficacy of telmisartan in the treatment of senile essential hypertension (EH). Methods Eighty elderly EH patients were treated with telmisartan 80 mg once daily for 4 weeks. Results After 4 weeks of treatment, the blood pressure decreased significantly (166.25 ± 13.78) / 85.65 ± 85.65 mmHg before treatment and decreased to (130.34 ± 8.67) / (71.10 ± 6.28) mmHg after treatment (P < 0.01). Pulse pressure also significantly reduced (P <0.01), 24 hours ambulatory blood pressure calculated peak trough ratio> 65%. Conclusion Telmisartan is safe and effective in the treatment of elderly EH.