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异搏定是与罂粟硷相关的合成药,在1962年异搏定作为冠状动脉扩张剂被提出,以后又发现它具有肯定的抗心律失常作用,并选择性地对室上性心动过速具有疗效。虽然最初异搏定因其性质相似而归于β阻滞剂类的药物,后来证明它是在细胞膜的水平阻止钙内流。可能由于异搏定是较新的药物,在一些国家尚未应用,有关其毒性和付作用的临床报告还很少。我们报告这例是因自杀口服异搏定25片(总剂量2克)而致急性心脏中毒。它给我
Verapamil is a synthetic drug associated with papaverine, and verapamil was introduced as a coronary artery dilator in 1962 and was subsequently found to have affirmative anti-arrhythmic effects and to selectively have supraventricular tachycardia Efficacy. Although verapamil was originally classified as a β-blocker because of its similar properties, it was subsequently demonstrated that it inhibits calcium influx at the level of the cell membrane. Perhaps because verapamil is a newer drug, which has not been applied in some countries, there are few clinical reports on its toxicity and side effects. We report this case because of suicide oral verapamil 25 (total dose of 2 grams) and acute cardiotoxicity. It gives me