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目的筛选产褥感染产妇早期血清炎症敏感指标,为早期诊断提供参考。方法将42例产褥感染产妇作为观察组,留取其感染早期血清标本,并同时收集相近时期40名未发生感染产妇的血清标本作为对照组。比较两组WBC、PCT、hs-CRP、IL-6、IL-8和TNF-α的变化。结果观察组血清PCT(3.56±1.35)ng/m L、hs-CRP(13.72±3.19)mg/L、IL-6(87.04±33.59)pg/m L和TNF-α(97.52±33.19)pg/m L均分别高于对照组的(1.31±0.67)ng/m L、(7.21±1.47)mg/L、(45.18±17.23)pg/m L和(41.52±15.38)pg/m L(P<0.05)。结论产褥感染产妇早期血清PCT、hs-CRP、IL-6和TNF-α明显升高,可作为早期诊断与治疗的参考指标。
Objective To screen sensitive indicators of early maternal serum inflammation in puerperal infection and provide reference for early diagnosis. Methods 42 cases of puerperal infection mothers as the observation group, early infection of serum samples were collected, and at the same time collected 40 serum samples from infected women without infection as a control group. The changes of WBC, PCT, hs-CRP, IL-6, IL-8 and TNF-α were compared between the two groups. Results The serum PCT (3.56 ± 1.35) ng / m L, 13.72 ± 3.19 mg / L, 87.04 ± 33.59 pg / m L and 97.52 ± 33.19 pg / (1.31 ± 0.67) ng / m L, (7.21 ± 1.47) mg / L, (45.18 ± 17.23) pg / m L and (41.52 ± 15.38) pg / m L respectively in the control group, 0.05). Conclusions The serum PCT, hs-CRP, IL-6 and TNF-α levels of puerpera in early puerperal infection are significantly increased, which may serve as a reference for early diagnosis and treatment.