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以横断面调查为基础的镉在人体内蓄积及其毒理学作用的研究,难于反映体内镉负荷量及分布的动态变化。为此,作者对职业性接触镉工人进行了纵向研究。研究对象为37名在镉银合金生产中暴露于镉烟的男性工人。于1981年12月、1983年3月、1986年1月和1990年4月用免疫测定法测定尿β_2—微球蛋白和视黄醇结合蛋白,用石墨炉原子吸收光谱法测定血和尿镉,用快速
The cross-sectional investigation of cadmium accumulation in the human body and its toxicological role in the study, it is difficult to reflect the dynamic changes in the amount and distribution of cadmium in vivo. To this end, the authors conducted a longitudinal study of occupational exposure to cadmium workers. The study was conducted on 37 male workers exposed to cadmium smoke in the production of cadmium silver alloys. Urine β_2-microglobulin and retinol binding protein were determined by immunoassay in December 1981, March 1983, January 1986 and April 1990, and blood and urine cadmium were determined by graphite furnace atomic absorption spectrometry Use fast