论文部分内容阅读
目的 寻找检测乳腺癌前哨淋巴结(SLN)方法,研究前哨淋巴结活检(SLNB)预测腋窝淋巴结状况的准确性。方法 对40例乳腺癌患者行美蓝染色法检测SLN,并行腋窝淋巴结清扫术(ALND)后,将腋窝淋巴结转移状况与SLN进行对比分析,分析SLN检出率及临床特征。结果40例患者中成功检测出SLN 35例,成功率为87.5％。检出SLN 60个,平均每例检出SLN 1.7个。2例出现假阴性,假阴性率为10.5％,无假阳性。35例患者中有16例SLN阳性,阳性率为45.7％。SLNB预测腋窝淋巴结(ALN)的敏感性为88.8％,特异性为100％,准确性为94.4％。结论 美蓝染色法检测乳腺癌SLN经济实用,可以较准确地预测腋窝淋巴结的转移状况。
Objective To search for a method to detect sentinel lymph node (SLN) in breast cancer and investigate the accuracy of SLNB in predicting axillary lymph node status. Methods 40 cases of breast cancer patients were detected by methylene blue staining with SLN. After axillary lymph node dissection (ALND), the status of axillary lymph node metastasis was compared with that of SLN. The detection rate and clinical features of SLN were analyzed. Results Of 40 patients, 35 SLN cases were successfully detected with a success rate of 87.5%. Sixty SLNs were detected, with an average of 1.7 SLNs detected in each case. 2 cases of false negative, false negative rate of 10.5%, no false positive. Among the 35 patients, 16 were positive for SLN with a positive rate of 45.7%. The sensitivity of SLNB to predict axillary lymph nodes (ALN) was 88.8%, specificity was 100%, and accuracy was 94.4%. Conclusions The methylene blue staining method is an economical and practical method for the detection of breast cancer SLN, which can predict the metastasis of axillary lymph node more accurately.