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小儿原发性肾病综合征尽可能在发病早期,识别出是微小变化型抑或其它肾小球损害在临床上是很重要的。有关肾活组织检查、最好的初期治疗方法及判断予后都是根据这种区别而定。可以告诉微小变化型的双亲:予后好能完全恢复,不需要肾活组织检查,用强的松治疗对绝大部分的患儿能控制本病的症状及防止任何并发症。反之,对伴有其它肾小球损害的双亲,必须让其知道本病能发展为慢性肾功能不全,需要一次或多次的肾活组织检查,目前无有效疗法。很多有经验的临床医生,特别是在初期用
It is clinically important that children with primary nephrotic syndrome be diagnosed early in the disease as being small changes or other glomerular lesions. About the kidney biopsy, the best initial treatment and judgments are based on this difference. Can tell the tiny changes in the type of parents: good to be able to fully recover, do not need renal biopsy, with prednisone for the treatment of most children can control the symptoms of the disease and prevent any complications. Conversely, parents with other glomerular lesions must be aware that the disease develops chronic renal insufficiency and requires one or more renal biopsies. Currently, there is no effective treatment. Many experienced clinicians, especially in the early stages