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目的探讨联合采用米非司酮配伍米索前列醇和缩宫素预防中期妊娠引产出血的临床效果。方法抽取86例从2013年5月至2016年6月就诊于我院的中期妊娠产妇,在按随机原则将其分为传统组和特殊组,每组各43例。单独采用缩宫素对传统组产妇进行常规预防治疗,对特殊组产妇则在前者基础上添加米非司酮配伍米索前列醇进行联合治疗,对两组产妇的产后出血率以及产后2h和24h内的出血量进行研究比较。结果经相应性治疗后,特殊组产妇的产后出血率为2.33%,传统组产妇的产后出血率为13.95%,后组产妇的产后出血率大于前组产妇,且两者间的数据差异具有统计学意义(P<0.05)。结论在予以中期妊娠产妇进行常规预防引产出血治疗时,辅以米非司酮配伍米索前列醇进行双重治疗,可显著降低产妇的产后出血率并减少产后出血量,值得临床借鉴。
Objective To investigate the clinical effect of combined use of mifepristone and misoprostol and oxytocin in the prevention of induced abortion in mid-term pregnancy. Methods Totally 86 middle-term pregnant women who were treated in our hospital from May 2013 to June 2016 were randomly divided into the traditional group and the special group, with 43 cases in each group. Oxytocin alone conventional group of mothers for routine prevention and treatment of maternal special group is based on the former with mifepristone and misoprostol combined treatment of postpartum hemorrhage rate of the two groups of maternal postpartum and 2h and 24h The amount of bleeding within the study and comparison. Results After the corresponding treatment, the rate of postpartum hemorrhage was 2.33% in the special group and 13.95% in the traditional group. The postpartum hemorrhage rate in the latter group was higher than that in the former group, and the difference between the two groups was statistically significant Significance (P <0.05). Conclusions The double treatment with mifepristone and misoprostol can reduce the rate of postpartum hemorrhage and reduce the amount of postpartum hemorrhage. Therefore, it is worthy of clinical reference.