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目的探讨甲钴胺与硫辛酸联用对糖尿病周围神经病变患者神经传导速度的影响。方法将我院71例糖尿病周围神经病变患者随机分为对照组34例和治疗组37例,对照组肌注甲钴胺;治疗组给予甲钴胺+硫辛酸进行治疗。疗程结束后统计疗效,比较两组运动、感觉神经传导速度。结果治疗组总有效率明显高于对照组(P<0.05),两组神经传导速度较治疗前均有明显提高(P<0.05),治疗组对神经传导的改善优于对照组。结论甲钴胺联合硫辛酸治疗糖尿病周围神经病变的疗效确切,可有效减轻患者痛苦,值得临床推广。
Objective To investigate the effects of mecobalamin and lipoic acid on the nerve conduction velocity in patients with diabetic peripheral neuropathy. Methods 71 patients with diabetic peripheral neuropathy in our hospital were randomly divided into control group 34 cases and treatment group 37 cases, control group intramuscular mecobalamin; treatment group given mecobalamin + lipoic acid for treatment. After the end of treatment, statistical analysis was conducted to compare the motor and sensory nerve conduction velocities between the two groups. Results The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). The nerve conduction velocity was significantly increased in both groups (P <0.05). The improvement of nerve conduction in the treatment group was better than that in the control group. Conclusion Mecobalamin combined with lipoic acid treatment of diabetic peripheral neuropathy exact effect, which can effectively reduce the suffering of patients, is worth clinical promotion.