论文部分内容阅读
目的探讨肺癌骨转移的临床特点。方法对58例肺癌骨转移的临床资料进行回顾性分析。结果肺癌骨转移多发者占82.76%,单发者占17.24%;肺癌患者中腺癌发生骨转移占55.17%,鳞癌占31.03%,小细胞未分化癌占13.79%;骨转移的部位:胸部44.95%,脊柱25.76%,四肢11.62%,骨盆9.09%,颅骨7.58%。肺癌骨转移以多发为主,腺癌发生率最高,其次是鳞癌及小细胞癌。X线、CT、MR I检查提示骨转移以溶骨性骨破坏的占82.76%,成骨性骨破坏的占10.34%,混合性占6.90%。结论肺癌骨转移以多发性溶骨性骨破坏为特征,腺癌骨转移发生率最高,其次是鳞癌和小细胞癌。
Objective To explore the clinical features of bone metastases from lung cancer. Methods The clinical data of 58 patients with lung cancer with bone metastases were retrospectively analyzed. Results 82.76% of lung cancer patients with bone metastasis were multiple, 17.24% of them were single lesions. The incidence of bone metastasis was 55.17%, squamous cell carcinoma was 31.03%, and small cell undifferentiated carcinoma accounted for 13.79%. The site of bone metastasis was: chest 44.95%, 25.76% of the spine, 11.62% of the limbs, 9.09% of the pelvis, and 7.58% of the skull. The incidence of adenocarcinoma was highest in bone metastases of lung cancer, followed by squamous cell carcinoma and small cell carcinoma. X-ray, CT, and MR I examinations indicated that bone metastases accounted for 82.76% of osteolytic bone destruction, osteoblastic bone destruction accounted for 10.34%, and mixedness accounted for 6.90%. Conclusion The bone metastasis of lung cancer is characterized by multiple osteolytic bone destruction. The incidence of bone metastases in adenocarcinoma is the highest, followed by squamous cell carcinoma and small cell carcinoma.