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目的探讨羊膜腔内输液治疗妊娠中晚期羊水过少的临床疗效。方法回顾性分析本院近年来收治的53例中妊娠中晚期羊水过少的产妇临床资料,比较输液组与对照组的羊水情况,新生儿预后情况及剖宫产的指证。结果输液组24例经过AI治疗后,AFI增加了1.2～6.7 cm,脐血流S/D平均值由输液前的4.12降至输液后的2.84,差异有统计学意义(P<0.05)。其中15例患者输液治疗后,AFI≥8.0 cm,治疗的有效率62.5%,延长孕周3 d至5周,平均为3+2周。两组的新生儿死亡几率经统计学分析,差异无统计学意义,P>0.05。胎儿窘迫的发生几率也有差异性,P<0.05。结论羊膜腔内输液能减慢胎儿窘迫的发生率、降低剖宫产率,提高围产儿的存活率,是治疗妊娠中晚期羊水过少的安全、有效的办法。
Objective To investigate the clinical effect of amniotic fluid infusion in the treatment of oligohydramnios in late pregnancy. Methods The clinical data of 53 cases with oligohydramnios in the second and third trimester of pregnancy in our hospital were retrospectively analyzed. The amniotic fluid status, neonatal prognosis and cesarean section were compared between the infusion group and the control group. Results In the infusion group, the AFI increased by 1.2 ~ 6.7 cm in 24 cases after AI treatment. The mean S / D of cord blood flow decreased from 4.12 before infusion to 2.84 after infusion. The difference was statistically significant (P <0.05). Among 15 patients, AFI≥8.0 cm after infusion therapy, the effective rate of treatment was 62.5%, and gestational weeks were extended from 3 d to 5 weeks with an average of 3 + 2 weeks. Neonatal mortality in both groups was statistically analyzed, the difference was not statistically significant, P> 0.05. The incidence of fetal distress is also different, P <0.05. Conclusion Intra-amniotic fluid infusion can reduce the incidence of fetal distress, reduce the rate of cesarean section and improve the survival rate of perinatal. It is a safe and effective way to treat oligohydramnios in late pregnancy.