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目的研究柳州地区2012年1月-2016年3月阴道毛滴虫与人型支原体的共生情况和药敏回顾性分析,为临床合理使用药物提供依据。方法阴道毛滴虫采用超高倍显微镜镜检,支原体培养及药敏采用微量肉汤稀释法。结果365例感染阴道毛滴虫患者中133例感染人型支原体,感染率为36.4%,40例合并感染解脲支原体和人型支原体,感染率为11.0%。阴道毛滴虫合并人型支原体和人型支原体及解脲支原体混合感染对强力霉素、交沙霉素和美满霉素耐药率较低,对大环内酯类、喹诺酮类药物耐药率高。人型支原体对8种抗菌药物耐药比例最高,占25.6%;人型支原体及解脲支原体混合感染对6种抗菌药物耐药比例最高,占22.5%。结论柳州地区阴道毛滴虫和支原体的共生情况很普遍,临床中应注意合并治疗。
Objective To study the symbiosis and drug susceptibility of Trichomonas vaginalis between January 2012 and March 2016 in Liuzhou area and to provide a basis for clinical rational use of drugs. Methods Trichomonas vaginalis using ultra-high power microscopy, mycoplasma culture and drug sensitivity using broth microdilution method. Results Among the 365 cases of Trichomonas vaginalis infection, 133 cases were infected with Mycoplasma hominis, the infection rate was 36.4%, 40 cases were infected with Ureaplasma urealyticum and Mycoplasma hominis, the infection rate was 11.0%. Trichomonas vaginalis combined with Mycoplasma hominis and Mycoplasma hominis and Ureaplasma urealyticum infection doxorubicin, josamycin and minocycline drug resistance rate of macrolides, quinolone resistance rate high. Mycoplasma hominis had the highest rate of resistance to 8 kinds of antimicrobial agents, accounting for 25.6%. The mixed infection rate of Mycoplasma hominis and Ureaplasma urealyticum was the highest, accounting for 22.5%. Conclusions The symbiosis of Trichomonas vaginalis and Mycoplasma in Liuzhou is very common. Clinical treatment should be combined with treatment.