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目的探讨米非司酮辅助甲氨蝶呤对宫外孕患者治疗过程中的临床疗效。方法 100例宫外孕患者随机分为观察组和对照组,各50例。对照组患者使用常规甲氨蝶呤的方法进行治疗,观察组患者使用甲氨蝶呤联合米非司酮的方法进行治疗,两组患者在治疗完成后比较两组患者的治疗效果以及两组患者的阴道止血时间。结果两组患者在经过治疗后均有所好转,但观察组患者的治疗总有效率98%明显优于对照组患者的治疗总有效率80%,同时观察组患者的止血时间(11.23±1.34)d明显优于对照组患者的阴道止血时间(23.58±4.85)d,差异均具有统计学意义(P<0.05)。结论在对宫外孕患者进行治疗的过程中,使用甲氨蝶呤联合米非司酮的方法效果更佳,能够对患者进行及时有效的治疗,在临床上值得推广应用。
Objective To investigate the clinical efficacy of mifepristone-assisted methotrexate in the treatment of patients with ectopic pregnancy. Methods 100 cases of ectopic pregnancy were randomly divided into observation group and control group, 50 cases each. Patients in the control group were treated with methotrexate, patients in the observation group were treated with methotrexate and mifepristone, and the treatment effect was compared between the two groups after the treatment was completed, and the patients in both groups Vaginal bleeding time. Results Both groups improved after treatment, but the total effective rate in the observation group was 98%, which was significantly better than that in the control group (80%). The bleeding time in the observation group (11.23 ± 1.34) d was significantly better than the control group of patients with vaginal bleeding time (23.58 ± 4.85) d, the differences were statistically significant (P <0.05). Conclusion During the treatment of patients with ectopic pregnancy, the combination of methotrexate and mifepristone is more effective and can treat the patients timely and effectively, which is worthy of popularization and application in clinic.