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现代制药工业仅有65年的历史,但在此段时期里,它不断地提供感染性疾病的克星,如磺胺、青霉素、头孢、氨基糖甙、喹诺酮及其它类药物,使医疗实践更具革命性,一些曾公认为威胁人类生命的疾病如天花已被消灭,病人平均住院时间缩短.在美国,抗菌药物的开发,每试验6000个化合物才有一个可能上市,需多年的人力、财力的投入,甚至达17年之久,尽管如此,美国制药厂家为适应新药市场的要求,近年来大大增加对此类新药研究和开发的投资.
The modern pharmaceutical industry has only 65 years of history, but during this period it continues to provide nemesis for infectious diseases such as sulfa, penicillin, cephalosporins, aminoglycosides, quinolones, and other drugs that revolutionize medical practice Some of the diseases that have been recognized as a threat to human life, such as smallpox, have been eliminated and the average hospitalization time has been shortened. In the United States, the development of antimicrobial drugs has only one investment of 6,000 compounds per test-day, which may take many years of manpower and financial resources , Even up to 17 years. However, in order to meet the requirements of the new drug market, the U.S. pharmaceutical manufacturers have greatly increased their investment in such new drug research and development in recent years.