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目的：探讨治疗晚期肿瘤病人的原发灶和消除因肿瘤转移而引起的骨疼痛，提高病人的生存质量。方法：采用大剂量顺铂（ＤＤＰ）为主的联合化疗方案，治疗１６例晚期恶性肿瘤骨转移患者。结果：该方案对原发灶的近期有效率为４３％，而对疼痛和活动受限改善的有效率分别为９４％和８８％。结论：采用以大剂量顺铂为主的联合化疗方案治疗晚期肿瘤病人，不仅对肿瘤原发灶有一定的疗效，而且对消除因肿瘤骨转移引起的骨痛和提高病人的生存质量方面也有很好的效果
Objective: To explore the treatment of primary tumors in patients with advanced cancer and to eliminate the bone pain caused by tumor metastasis and improve the patient’s quality of life. Methods: Sixteen patients with advanced malignant bone metastases were treated with high-dose cisplatin (DDP)-based combination chemotherapy. RESULTS: The short-term efficacy of this protocol for the primary tumor was 43%, while the effective rate for pain and mobility limitation improvement was 94% and 88%, respectively. Conclusion: The use of high-dose cisplatin-based combination chemotherapy regimen for advanced cancer patients not only has a certain effect on the primary tumor, but also has a very good effect on eliminating the bone pain caused by tumor bone metastasis and improving the patient’s quality of life. Good results