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多发性硬化(Multiple sclerosis)是一种慢性神经系统疾病,发病多在壮年,其症状与体征非常复杂而多变,病程中反复发作与自然缓解为其临床特征;其病理变化为:先在脑或脊髓白质中发生广泛而散在的神经纤维髓鞘崩解,后来轴突亦遭破坏,最后由神经胶质修補形成瘢痕,由之而得多发性硬化之名。本病在19世纪初叶首由Carswell,Cruveilhiser及Frerichs等氏(1)在病理方而加以纪载,同世纪的后期Charcot氏(1.2)又对本病加以详述,并从其极
Multiple sclerosis is a chronic nervous system disease, the incidence of mostly in the prime of life, the symptoms and signs are very complex and varied, the course of the disease recurrent and natural relief for its clinical features; its pathological changes: first in the brain Or spinal cord white matter occurred in a wide range of scattered and scattered nerve fiber myelin disintegration, and later also damaged axons, and finally formed by the glial scar repair, resulting from the name of multiple sclerosis. The disease was first reported by Carswell, Cruveilhiser, and Frerichs et al. (1) in pathology in the early 19th century. Charcot’s (1.2) later in the same century described this disease in greater detail