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胎儿宫内发育迟缓（ＩＵＧＲ）的围产期死亡率及患病率均较高。随着围产医学的发展，ＩＵＧＲ越来越受到产科及新生儿科的重视。它可由多种原因引起，宫内感染是造成ＩＵＧＲ的一个重要原因。据报道由感染引起的ＩＵＧＲ发生率为７．５％，感染造成ＩＵＧＲ与母儿的免疫状态、遗传因素、初次病毒血症及免疫反应出现早晚、胎儿自身发育状况、子宫暴露于病原的时间有关，ＩＵＧＲ的类型与感染的时期有关。绝大多数报道都认为母亲感染通过影响胎盘功能而造成ＩＵＧＲ，也有由细菌、病毒毒素作用于胎儿造成胎儿细胞数目减少、活力降低甚至早亡或染色体改变造成ＩＵＧＲ及畸形。对于ＩＵＧＲ的临床表现及治疗进展本文也作了简要介绍，了解上述情况有助于预防ＩＵＧＲ的发生。
Infant intrauterine growth retardation (IUGR) perinatal mortality and prevalence were higher. With the development of perinatal medicine, IUGR is increasingly valued by obstetrics and neonatology. It can be caused by a variety of causes, and intrauterine infection is an important cause of IUGR. It has been reported that the incidence of IUGR caused by infection is 7.5%. The infection causes the IUGR to be related to the immune status of mother and child, genetic factors, first viremia and the appearance of immune reaction sooner or later, fetal self-development status and time of uterine exposure to pathogens The type of IUGR is related to the period of infection. Most reports suggest that mother’s infection causes IUGR through affecting placental function. There are also bacterial, viral toxins that cause a reduction in the number of fetal cells, decreased or even premature death, or chromosomal alterations that cause IUGR and deformity. IUGR for the clinical manifestations and treatment of this article also made a brief introduction to understand the above situation will help prevent the occurrence of IUGR.