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本研究旨在应用运动训练过的动物的离体冠脉标本,包括近端冠状动脉(直径>2mm)、近似阻力动脉(直径150～250μm)及阻力小动脉,来评估运动训练对冠脉平滑肌紧张性功能的影响。 方法 采用25～40kg重的成年雌性小型猪,使其熟悉踏车运动,每批8头猪随机平分为训练组(ET组)和对照组(SED组)。后者被关于6×10英尺的围栏中,前者第1周在活动平板上按3mph,0％坡度×20～30min(耐力)和5mph×15min(快跑)进行,奔跑的速度和时间按每1头猪的耐受性逐渐增加,至12周时,典型的训练时间为85min,其中2.5 mph×5min作准备活动,5～8 mph×15
The purpose of this study was to evaluate the effect of exercise training on coronary artery smooth muscle (SMA) activity in isolated coronary artery specimens of exercise-trained animals, including proximal coronary arteries (diameter> 2 mm), approximate resistance arteries (150-250 μm diameter), and resistance arteries Effects of stressful function. Methods 25 - 40kg adult female miniature pigs were used to make them familiar with treadmill exercise. Eight pigs in each batch were randomly divided into training group (ET group) and control group (SED group). The latter was placed on a 6 x 10 foot fence, with the former performing 3mph, 0% slope 20-30min (endurance) and 5mph 15min The tolerability of 1 pig increased gradually. At 12 weeks, the typical training time was 85 min, of which 2.5 mph × 5 min was for preparation and 5 to 8 mph × 15