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近年来国内外对噻吗心安的临床研究和应用日渐增多,其优越的降眼压效果已得到普遍证实。我国自行合成的噻吗心安正在进行临床试用,据杨国华等(1982)报告,青光眼病人用国产噻吗心安点眼有较好的降压效果,而国产药对正常眼压降压效果和机理的实验研究尚未见报导。为此,我们在临床应用之前以正常家兔为对象,对国产噻吗心安点眼后降压作用时间、降压幅度、持续时间等进行观察,并用
In recent years, clinical studies and applications of timolol at home and abroad are increasing, and its superior hypoglycemic effect has been generally confirmed. According to Yang Guohua et al. (1982), there is a good antihypertensive effect of domestic timolol eye spots in patients with glaucoma, and the experiment and effect of domestic drug on the antihypertensive effect and mechanism of normal intraocular pressure Research has not been reported yet. To this end, we use normal rabbits before clinical application of timolol domestic point after the eye time of antihypertensive effect, the magnitude of the antihypertensive, duration were observed and used