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目的 :探讨临床上使用非不司他治疗慢性肾病伴高尿酸血症的临床效果。方法 :我们对2014年5月-2015年8月期间我院收治的58例慢性肾病伴高尿酸血症患者的临床资料进行回顾性研究。我们按照随机分配的原则将这58例患者随机分为实验组和对照组,每组各有29例患者。我们对实验组患者使用非不司他进行治疗,对对照组患者使用传统的别嘌醇治疗,并对两组患者的血尿酸、肝肾功能以及血常规进行定期检查和治疗,并对患者进行定期随访。结果:经过治疗,两组患者的血尿酸水平较基线水平均有明显下降,且均具有统计学意义(P<0.05);实验组患者的血尿酸水平较对照组患者来说下降的程度更明显,二者相比差异具有显著性(P<0.05)。结论 :临床上使用非不司他治疗慢性肾病伴高尿酸血症的临床效果显著,患者的满意度较高,此方法值得在临床上进一步推广应用。
Objective: To investigate the clinical effect of non-fascix treatment of chronic kidney disease with hyperuricemia. Methods: We retrospectively reviewed the clinical data of 58 patients with chronic kidney disease and hyperuricemia who were admitted to our hospital from May 2014 to August 2015. In accordance with the principle of random allocation of these 58 patients were randomly divided into experimental group and control group, each group of 29 patients. We treated patients in the experimental group with non-finasteride, patients in the control group received conventional allopurinol treatment, and routinely examined and treated for blood uric acid, liver and renal function, and blood routine in both groups, and performed the patients Regular follow-up. Results: After treatment, serum uric acid levels in both groups were significantly lower than those in baseline group (P <0.05). The level of serum uric acid in the experimental group decreased more significantly than that in the control group , The difference between the two was significant (P <0.05). Conclusion: The clinical effect of using non-capostat in the treatment of chronic nephropathy with hyperuricemia is significant and the patient satisfaction is high. This method deserves further clinical application.