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以往认为,脑缺血后迟发性神经元死亡(ｄｅｌａｙｅｄｎｅｕｒｏｎａｌｄｅａｔｈ,ＤＮＤ)主要是一种被动的坏死过程,近年来的资料表明主动的细胞凋亡与ＤＮＤ紧密相关[1]。但目前对脑缺血后细胞凋亡的分子机制尚不清楚。全脑缺血后ＤＮＤ与ｐ53、ｐ21基因是否有关以及这两者之
In the past, delayed neuronal death (DND) after cerebral ischemia is mainly a passive necrosis process, recent data indicate that active apoptosis is closely related to DND [1]. However, the molecular mechanism of apoptosis after cerebral ischemia is still unclear. Is DND associated with p53 and p21 after global cerebral ischemia and both?