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为了调查广州市原发性肝癌（PHC）的病因因素，本研究对100例原发性肝癌作了病例对照研究。单因素分析表明，HBV感染与PHC关系最密切。此外，HCV感染、社会心理因素、肝炎家族史、单独厨房及抽油烟机的缺乏、食鱼生食物可能与PHC的发生有关。logistic多因素分析表明，HBV感染、HCV感染、负性事件、单独厨房、食鱼生食物与广州地区PHC的发生有关。值得注意的是以上因素间的协同作用，尤以HBV与其他因素间的协同作用更为明显。
In order to investigate the etiological factors of primary hepatocellular carcinoma (PHC) in Guangzhou, a case-control study of 100 primary hepatocellular carcinomas was conducted in this study. Univariate analysis showed that HBV infection was most closely related to PHC. In addition, HCV infection, psychosocial factors, family history of hepatitis, lack of separate kitchens and range hoods, and dietary foods may be related to the development of PHC. Logistic multivariate analysis showed that HBV infection, HCV infection, negative events, kitchen, eating raw food and Guangzhou area PHC related. It is worth noting that the synergy between the above factors, especially the synergy between HBV and other factors is more obvious.